P.U.V.A.- Photochemotherapy of psoriasis with oral 8: Methoxypsoralen and long wave ultra violet radiation
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منابع مشابه
Bath-water PUVA therapy with 8-methoxypsoralen in mycosis fungoides.
PUVA therapy is widely used for early stage mycosis fungoides. While the efficacy of PUVA with oral 8-methoxypsoralen (8-MOP) is well documented, the use of its topical variation, bath-water PUVA therapy with 8-MOP has not been studied. The purpose of this study was to assess the effect of 8-MOP bath-water PUVA therapy in adult patients with early stage mycosis fungoides. We retrospectively eva...
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Severe, or even lethal, cellular damage can follow the conjoint action of a chemical photosensitizer and effective frequencies of the electromagnetic spectrum. The fact that bacteria, as well as other cellular systems, are subject to photosensitization by such compounds as methylene blue was known fifty years ago (Reitz, 1908). The relatively limited number of studies of bacterial photosensitiz...
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BACKGROUND Dihydroxyacetone (DHA), a colorless sugar in "sunless" tanning lotions, binds to stratum corneum to form a UV-A-protective brown pigment. Bound DHA polymer is shed faster from hyperproliferative skin sites such as psoriatic plaques. We tested the hypothesis that selective shedding of DHA pigment during psoralen-UV-A (PUVA) treatment of psoriasis may allow higher UV-A doses, thus acce...
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BACKGROUND There are unpredictable inter-individual differences in sensitivity to psoralen-UVA (PUVA) photochemotherapy, used to treat skin diseases including psoriasis. Psoralens are metabolised by cytochrome P450 enzymes (P450), and we hypothesised that variability in cutaneous P450 expression may influence PUVA sensitivity. We previously showed that P450 CYP1B1 was abundantly expressed in hu...
متن کاملAntiproliferative, antiangiogenic and apoptotic effect of photochemotherapy (PUVA) in psoriasis patients.
The aim of the study was to investigate the antiproliferative, antiangiogenic and apoptotic effect of photochemotherapy (PUVA) in psoriatic patients, and to compare it with a control group of psoriatics treated with local corticosteroid therapy. The study included 60 psoriasis patients, 30 of them allocated to PUVA therapy and local corticosteroid each. Immunohistochemical methods of staining w...
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ژورنال
عنوان ژورنال: South African Journal of Physiotherapy
سال: 1981
ISSN: 2410-8219,0379-6175
DOI: 10.4102/sajp.v37i1.770